More Zika in the US as RNA vaccine gets funding

first_imgWhile many countries in the Americas are reporting a slowing of Zika transmission, the United States is seeing an increased rate in Florida. In other disease news, an RNA vaccine gets funding while a new study suggests the usefulness of IgM Zika testing for babies.More Zika in Caribbean, USThe Pan American Health Organization (PAHO) released a new Zika situation report yesterday, noting that since the last report published on Sep 22, no new countries or territories have reported transmission of the mosquito-borne illness. Forty-seven countries or territories in the Americas have confirmed Zika transmission, with five countries reporting sexual transmission of the virus.Mexico is continuing its downward trend of reported transmissions, while the United States is seeing an increase in cases, mostly in Florida. Puerto Rico is also reporting a downward trend, as are countries in Central America.Caribbean island nations that recently reported their first cases of Zika have noted increasing transmission trends, including St. Barthelemy and St. Martin.No new countries reported microcephaly or cases of other congenital malformations, leaving that number at 16. A new country, Guadalupe, reported its first case of Guillain-Barre syndrome (GBS), while Puerto Rico reported its second death caused by Zika-related GBS.Yesterday the Florida Department of Health, Florida Health, reported one new case of Zika in a non-Florida resident who visited the Miami Beach neighborhood, but not new cases today. Now 18 non-Florida residents have been infected in Florida. Earlier this week, officials reported that despite extensive spraying, Zika mosquitoes were still being found in Miami Beach.Funds for RNA vaccineYesterday the Infectious Disease Research Institute (IDRI) announced it received $491,000 from the National Institute of Allergy and Infectious Diseases to develop an RNA-based Zika vaccine over the next 2 years.RNA-based vaccines use the genetic makeup of the virus and synthetic materials, which allows them to be manufactured quickly, according to an IDRI news release.”This is a method of hijacking the virus’s own machinery to express proteins in order to rapidly make a safe and effective vaccine,” said Dan Stinchcomb, PhD, senior vice president for vaccine development viral disease at IDRI. “RNA encoding protein antigens can be rapidly synthesized and manufactured … When delivered, the RNA vaccine can effectively induce protective immune responses quickly.”IDRI said the grant allows the company, in addition to devleloping the Zika vaccine, to perform proof-of-concept studies that could be applicable to other emerging infectious disease vaccines.Study recommends IgM testing in infantsFinally, a study yesterday in the Journal of Infectious Diseases adds to the mounting evidence that Zika virus infection causes congenital disease in utero. Brazilian researchers performed Zika virus (ZIKV) immunoglobulin M (IgM) tests on the blood and cerebrospinal fluid (CSF) of 42 mothers and their babies with microcephaly. IgM does not cross the placenta, so it’s a useful indicator of ZIKV infection in neonates.In the babies, 38 (90.5%) had positive ZIKV-IgM, when considering both blood and CSF test results. The ZIKV-IgM was higher in CSF (median, 14.9) than in blood serum (median, 8.9). According to the authors, all ZIKV-IgM–positive results in the infants were confirmed by the presence of neutralizing antibodies.The results led the authors to recommend ZIKV IgM testing in neonates with suspected Zika-related congenital malformations.See also:Oct 6 PAHO updateOct 6 Florida Health updateOct 6 IDRI news release Oct 6 J Infect Dis studylast_img read more

Contracts awarded for Belgrano Phase 3

first_imgARGENTINA: Infrastructure authority Trenes Argentinos Infraestructura has awarded contracts to undertake Phase 3 of the track renewals programme on the 1 000 mm gauge Belgrano network.Divided into four lots worth 3∙5bn pesos, Phase 3 covers 300 km including route C12 from Joaquín V González to Metán, as well as route C8 from Metán to Las Cejas. In total, 217 km are to be upgraded in the province of Salta, 16 km in Santiago del Estero and 67 km in Tucumán.‘When the work is complete in 2019, we are going to have much more competitive logistics which is going to help the economy of the whole of northwest Argentina to develop’, said Trenes Argentinos Infraestructura President Guillermo Fiad.last_img

Grand Haven boys lose early lead, fall to East Kentwood 63-54 in O-K Red game

first_img Franklin Sports MLB Electronic Baseball … Inappropriate / Offensive $0.00 Inappropriate / Offensive Other Add Comments (Max 320 characters) Ads by Amazon Share (1862) Thank you! This will help us improve your ad experience. We will try not to show you such ads again. Bestseller Dude Perfect Signature Bow Nerf Sports Bi… Bestseller Other DEAL OF THE DAY (33138) Thank you! This will help us improve your ad experience. We will try not to show you such ads again. Bestseller × Mail ENDS IN DEAL OF THE DAY Displayed poorly Report a problem This item is… By Jacob ArvidsonLocalSportsJournal.comGRAND HAVEN – The Grand Haven Buccaneers faced a tough conference matchup at home on Tuesday night against a talented and athletic East Kentwood squad.Grand Haven trailed for the majority of the contest and fell 63-54 to the Falcons. The loss drops the Bucs to 7-2 overall and 1-1 in the O-K Red Conference.Zac Holman drives the lane for Grand Haven against East Kentwood guard No. 12 Justin Lary. Photo/Tim Reilly“In general, our execution tonight wasn’t great on either side of the ball,” said Grand Haven head coach Greg Immink. “Defensively, I thought we missed some assignments that we haven’t missed. We’ve got to go back to the drawing board and execute that stuff better.”Seniors Ross Koella and Zac Holman did all they could to save the Bucs, combining for 12 points in the fourth quarter to help cut a 14-point deficit to just seven late in the game, but East Kentwood was able to weather the storm.Koella finished with 19 points and eight rebounds, while Holman added 17 points.“They’ve been doing that for us all year,” Immink said. “They’re seniors who’ve put in a lot of time already on varsity. They’re experienced players and that’s what we expect from them.”Koella’s dunk late in the first quarter, after a steal by teammate Kellum Bridgeforth, gave the Bucs a 13-11 lead and seemed to swing the momentum in their favor. But that turned out to be Grand Haven’s last lead.A four-point play from East Kentwood’s Ylber Sahitolli, as the first quarter expired, sent the momentum back the other way.Grand Haven forward Ross Koella goes up for the baby hook in the lane. Photo/Tim ReillyThe Falcons led 28-24 at halftime and 45-35 after three quarters. They increased their edge to 14 points, 49-35, with about five minutes left, which proved to be enough to secure the win.Ca’Nas Coleman made sure the Falcons kept their lead by registering a double-double with 25 points and 10 rebounds.“He had a very nice ball game,” Immink said about Coleman. “He got some confidence when he knocked down those two threes to start, and then he’s just a load around the rim. He gets his hands on everything. Putbacks and drop-off passes, he was able to convert those tonight.”The schedule only gets tougher for Grand Haven. The Bucs have a week to prepare for West Ottawa, the defending O-K Red Conference champion.“They’re a veteran team,” Immink said. “They’ve got a lot of guys that played a lot of minutes last year as underclassmen and they’re as good as anybody around right now. It’s going to take a big effort from us at their place on Tuesday to see if we can get back in the win column.” ENDS IN Displayed poorly Other Not relevant DEAL OF THE DAY Displayed poorly Displayed poorly Thank you! This will help us improve your ad experience. We will try not to show you such ads again. DEAL OF THE DAY Add Comments (Max 320 characters) DEAL OF THE DAY Thank you! This will help us improve your ad experience. We will try not to show you such ads again. Report a problem This item is… Bestseller Bestseller Report a problem This item is… Displayed poorly Not relevant ENDS IN Thank you! 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Inappropriate / Offensive ENDS IN Share Fox Sports Go ENDS IN × (1009) × Report a problem This item is… Inappropriate / Offensive ENDS IN Not relevant × Report a problem This item is… Report a problem This item is… The League Add Comments (Max 320 characters) × Inappropriate / Offensive Add Comments (Max 320 characters) Other (8187) $3.99 A Warrior’s Heart Other Not relevant Inappropriate / Offensive Shop Now Add Comments (Max 320 characters) Not relevant (22) Add Comments (Max 320 characters) Other Other Range: Why Generalists Triumph in a Special… $14.99 Bestseller (35539) DEAL OF THE DAY Shares Ads by Amazon $26.86$49.99 Displayed poorly Not relevant $15.29$17.99 Other × Add Comments (Max 320 characters) (1461) Thank you! This will help us improve your ad experience. We will try not to show you such ads again. (124) $0.00 Thank you! This will help us improve your ad experience. We will try not to show you such ads again. $59.99 Report a problem This item is…last_img read more

Mass grave unearthed in Baghdad

first_img 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREStriving toward a more perfect me: Doug McIntyre The remains were placed in black plastic bags and transferred to a Shiite mosque in Dora, according to a police officer at the mosque. He spoke on condition of anonymity because he was not authorized to release information. An Associated Press photographer at the Kazimain mosque counted 33 plastic bags, and police said each bag held the remains of one victim. BAGHDAD – Remains of possibly dozens of people believed slain in sectarian violence were unearthed Saturday from a mass grave in a former al-Qaida stronghold in southern Baghdad – the third such find in Iraq this month. Also Saturday, an Iraqi television station reported one of its reporters had been kidnapped – the latest in a grim series of attacks that has made Iraq among the world’s most dangerous countries for journalists. The badly decomposed remains were found in Baghdad’s mostly Sunni Dora neighborhood by Sunnis who have turned against al-Qaida in Iraq, police said. They were discovered in an area overlooking the main highway leading to Shiite shrine cities in the south. Sunni extremists would often waylay travelers along that road, kidnapping and killing Shiites. last_img read more

Artificial Intelligence: What Will Algorithms Teach Us?

first_imgArtificial Intelligence took a giant leap forward recently with new research announced by Google. The new algorithm is self-learning  and tries to solve problems by assigning rewards and penalties based no the results of each trial. AI algorithms typically work by being fed massive amounts of data created by human domain experts or professionals. Standard algorithms fathom the best techniques from the pre-existing data.  The result of standard AI is to create a well-trained algorithm that can perform as well as the best human.The thing that is different about Google’s most recent work is that the algorithm is self-training.  Rather than just mimic what humans have done, the algorithm works through problems totally on its own. The results are fascinating.Google tested their algorithm with the game of Go. The algorithm re-discovered common moves used by the best players of the game.  After 20 days of training the algorithm became a far stronger player than any human. Interestingly the algorithm discovered advanced moves that haven’t been seen before. The algorithm is, in  a sense, able to teach humans how to play Go better.David Silver, AlphaGo’s lead researcher, said that “it’s more powerful than previous approaches because by not using human data, or human expertise in any fashion, we’ve removed the constraints of human knowledge and it is able to create knowledge itself.”last_img read more

ASF Grants 4 Grassroots

first_imgGrants are available for innovative ideas to increase participation in grassroots and community based sport.  The Australian Sports Foundation (ASF) has launched its Grants 4 Grassroots (G4G) Fund, a newly established small grants program funding innovative initiatives and programs aimed at increasing participation in grassroots and community based sport.G4G was set up to support non-profit organisations with a sporting purpose and sporting clubs throughout Australia. Grants ranging from $2,500-$10,000 will be made to support a variety of participation based projects such as the purchase of sporting equipment, sport development initiatives or improvements to sporting facilities.  Funds raised for G4G come from generous donors who wish to see more people playing sport and benefiting from the enjoyment and positive social impacts that sport can have on people and their communities.  Each year, the grant round will focus on a particular idea or theme and for 2014 the core objective is“Innovative community or grassroots projects which will increase youth participation in sport.” (Innovation is defined as making changes to encourage participation in your sport by introducing new methods, ideas, or products) To find out more information and to apply, please visit Applications close at 5pm on Friday, 16 May. Related LinksGrants 4 Grassrootslast_img read more

10 months agoMan City boss Guardiola: We must finish better against Liverpool

first_imgMan City boss Guardiola: We must finish better against Liverpoolby Paul Vegas10 months agoSend to a friendShare the loveManchester City boss Pep Guardiola has warned his players they must take their chances when they face Liverpool.Guardiola was speaking after victory at Southampton.”We missed a lot of chances. The game could’ve been six or seven. We have to score (more),” he said.”Liverpool are not going to give us this amount of chances. I’ve always had this feeling. We scored 106 goals last season – the best ever – but I thought we had to score more.”In every department I think we can improve. I said that two months ago when everybody said how beautiful and how handsome we were. There were many things I liked today.” About the authorPaul VegasShare the loveHave your saylast_img read more

Gov’t to Invite Thai Boys and Coach on All-Expense Paid Vacation

first_imgThe Government of Jamaica will be inviting the 12 boys from a youth soccer team in Thailand and their coach, who were recently rescued from a flooded cave, to vacation in the island, all expenses paid.Minister of Tourism, Hon. Edmund Bartlett, who made the announcement on Wednesday (July 18), said he “couldn’t think of a more appropriate gesture for these brave and extraordinary young men than to have them come and enjoy our beautiful island home”.“We will be using all our diplomatic channels through the Ministry of Foreign Affairs and Foreign Trade, also the Jamaican Honorary Consulate in Bangkok, Thailand, to try and make this a reality,” he said.“This will be an all-expense paid vacation and something that we are happy to do as part of the international community and to show appreciation for the special friendship we have had with the people of Thailand over the years,” Minister Bartlett added.The 12 boys, aged 11 to 16, and their 25-year-old coach had been trapped in the Tham Luang Nang Non cave system since June 23.The world was transfixed by the daring rescue of the boys from the flooded caves, which was undertaken by a team of international divers over three days from July 8 to 10.last_img read more